Article: Activation of alpha1-adrenoceptors increases firing frequency through protein kinase C in pyramidal neurons of rat visual cortex.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Kobayashi M; Sasabe T; Shiohama Y; Koshikawa N Neurosci. Lett., 2008
Table 1The effects of phenylephrine, isoproterenol and phorbol ester on the resting membrane potential, input resistance and properties of action potential
aMedium-duration afterhyperpolarization.*P<0.05 (paired t-test).**P<0.01 (paired t-test).***P<0.001 (paired t-test).
Resting membrane potential (mV) | Input resistance (MΩ) | Action potential amplitude (mV) | Half-duration (ms) | mAHPa amplitude (mV) | Half-duration (ms) | |
Control | −71.5±1.3 | 38.4±2.6 | 97.8±2.2 | 1.7±0.1 | 0.9±0.2 | 51.0±9.9 |
Phenylephrine | −68.9±1.9* | 40.6±3.9 | 93.1±3.2* | 1.8±0.1** | 1.0±0.3 | 44.5±13.2 |
n | 30 | 28 | 23 | 22 | 22 | 13 |
Control | −71.6±1.0 | 45.6±4.7 | 100.0±1.9 | 1.7±0.1 | 1.4±0.3 | 77.1±13.8 |
Isoproterenol | −65.8±1.6*** | 46.3±4.5 | 88.9±3.8*** | 1.9±0.1** | 1.2±0.3 | 38.8±10.7* |
n | 25 | 22 | 20 | 18 | 20 | 11 |
Control | −70.2±1.3 | 45.1±6.9 | 98.7±1.8 | 1.9±0.1 | 1.3±0.4 | 46.1±16.1 |
Phorbol ester | −71.2±1.3 | 65.3±12.3* | 91.2±2.9 | 1.8±0.1 | 2.0±0.3 | 76.2±14.3 |
n | 13 | 10 | 9 | 8 | 9 | 8 |